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Electrophysiological evidence for afferent nerve fibers in human ventral roots
Author(s) -
Phillips Lawrence H.,
Park T.S.,
Shaffrey Mark E.,
Shaffrey Christopher L.
Publication year - 2000
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(200003)23:3<410::aid-mus13>3.0.co;2-8
Subject(s) - rhizotomy , electrophysiology , sural nerve , anatomy , neuroscience , sensory system , afferent , dorsum , nerve root , dorsal root ganglion , spastic , sensory nerve , biology , medicine , cerebral palsy , psychiatry
This study was designed to test the hypothesis that ventral roots in humans contain afferent nerve fibers. We made direct electrophysiological recordings of compound nerve action potentials in dorsal and ventral roots in children undergoing selective dorsal rhizotomy for spastic cerebral palsy. We stimulated the saphenous or sural nerves, which are pure sensory nerves, with electrical stimuli while systematically recording from ventral and dorsal roots from L3 to S2. In addition to the dorsal root nerve action potentials which we expected, we found smaller compound nerve action potentials, which were clearly afferent, in the ventral roots. This confirms the limited amount of experimental evidence that ventral roots do contain some afferent nerve fibers. The functional significance of these observations is not yet clear. © 2000 John Wiley & Sons, Inc. Muscle Nerve 23: 410–415, 2000