Premium
Complex repetitive discharges: Cause or effect of neurogenic muscle hypertrophy?
Author(s) -
Rowin Julie,
Meriggioli Matthew N.
Publication year - 1999
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199911)22:11<1603::aid-mus20>3.0.co;2-q
Subject(s) - biceps , muscle hypertrophy , spinal muscular atrophy , medicine , anatomy , atrophy , sma* , brachialis , muscle atrophy , electromyography , physical medicine and rehabilitation , cardiology , skeletal muscle , mathematics , disease , combinatorics
We report a patient with adult‐onset spinal muscular atrophy (SMA) of the scapulohumeral type with neurogenic muscle hypertrophy (NMH) in markedly weakened biceps muscles in association with continuous complex repetitive discharges (CRDs). This is an apparently unique case due to the bilaterality of the NMH associated with CRDs as well as the well‐circumscribed symmetric upper extremity distribution of the hypertrophy. The possible mechanisms of NMH in association with spontaneous motor activity are discussed. © 1999 John Wiley & Sons, Inc. Muscle Nerve 22: 1603–1606, 1999