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M‐wave changes after high‐ and low‐frequency electrically induced fatigue in different muscles
Author(s) -
Badier Monique,
Guillot Chantal,
Danger Cédric,
Tagliarini Ferdinand,
Jammes Yves
Publication year - 1999
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199904)22:4<488::aid-mus10>3.0.co;2-y
Subject(s) - muscle fatigue , lactic acid , calcium , medicine , potassium , stimulation , chemistry , soleus muscle , muscle contraction , endocrinology , electromyography , skeletal muscle , biology , physical medicine and rehabilitation , organic chemistry , bacteria , genetics
The mechanisms of fatigue‐induced changes in evoked compound muscle action potential (M‐waves) are not well documented. In rats, isolated fast‐glycolytic (tibialis anterior, or TA) and slow‐oxidative muscles (soleus, or SOL) were stimulated repetitively at a low (10‐Hz) or high (80‐Hz) rate. Decreased amplitude and prolonged duration of M‐waves were only significant after high‐frequency fatigue in TA and SOL muscles; that is, in the conditions in which an influx of calcium was measured. On the other hand, maximal force failure and maximal lactic acid increase in the bath medium occurred in TA muscle after high‐ and low‐frequency fatigue trials. Postfatigue increase in potassium concentration occurred in all circumstances. Thus, M‐wave alterations depend mainly on the stimulation paradigm and not on the muscle type, and cannot be used as a marker of changes in intracellular potassium or lactate ions. This amplifies understanding of the significance of M‐wave changes in human exercise protocols. © 1999 John Wiley & Sons, Inc. Muscle Nerve 22: 488–496, 1999.