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Neuropathy in two cobalamin‐deficient breast‐fed infants of vegetarian mothers
Author(s) -
Renault Francis,
Verstichel Patrick,
Ploussard JeanPierre,
Costil Jean
Publication year - 1999
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199902)22:2<252::aid-mus13>3.0.co;2-d
Subject(s) - cobalamin , medicine , breast feeding , pediatrics , endocrinology , vitamin b12
We describe the electrophysiological findings in 2 infants with deficient cobalamin intake. After normal development, psychomotor regression appeared after the 6th month, leading to severe hypotonia and apathy before the 12th month. Electrodiagnostic evaluation showed sensory neuropathy in both cases, associated with motor neuropathy in 1 case. Thus, in an acquired floppy infant syndrome, electrophysiological signs of peripheral neuropathy contributed to the diagnosis of a curable metabolic disorder. © 1999 John Wiley & Sons, Inc. Muscle Nerve 22: 252–254, 1999