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Effects of training on exercise‐induced muscle damage and interleukin 6 production
Author(s) -
Croisier J.L.,
Camus G.,
Venneman I.,
DebyDupont G.,
JuchmèsFerir A.,
Lamy M.,
Crielaard J.M.,
Deby C.,
Duchateau J.
Publication year - 1999
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199902)22:2<208::aid-mus8>3.0.co;2-b
Subject(s) - delayed onset muscle soreness , medicine , myoglobin , eccentric , eccentric exercise , physical therapy , muscle damage , physical exercise , endocrinology , physical medicine and rehabilitation , chemistry , physics , organic chemistry , quantum mechanics
To address the question of whether the increased plasma concentration of interleukin 6 (IL‐6) following strenuous muscular work could be related to exercise‐induced muscle damage, 5 moderately active male volunteers underwent two isokinetic exercise sessions in the eccentric mode, separated by a period of 3 weeks during which the subjects underwent five training sessions. Before training, exercise was followed by severe muscle pain (delayed‐onset muscle soreness; DOMS), and by significant increases in plasma IL‐6 level and serum myoglobin concentration (SMb) ( P < 0.001). After training, postexercise DOMS and SMb values were significantly lower than those measured before training. There was no significant difference between plasma IL‐6 levels measured at the same time points before and after training. We conclude that the hypothetical relationship between exercise‐induced muscle damage and increased postexercise levels of circulating IL‐6 is not substantiated by the present results. © 1999 John Wiley & Sons, Inc. Muscle Nerve 22: 208–212, 1999