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Postnatal development of nitric oxide synthase activity in fast and slow muscles of the rat
Author(s) -
Lincoln Jill,
Harb Rehab
Publication year - 1998
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199810)21:10<1344::aid-mus19>3.0.co;2-1
Subject(s) - nitric oxide synthase , soleus muscle , nitric oxide , endocrinology , medicine , neuronal nitric oxide synthase , chemistry , extensor digitorum longus muscle , anatomy , biology , skeletal muscle
Nitric oxide synthase (NOS) activity was measured in extensor digitorum longus (EDL) and soleus muscles during postnatal development in the rat. At 1 and 2 weeks of age, similar low levels were found in both muscles. After 2 weeks, activity increased significantly only in EDL. Adult NOS activity was significantly higher in EDL than soleus. Thus, the preferential expression of NOS in fast muscle only occurs once the adult pattern of motor activity is established. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:1344–1346, 1998.