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Normal postexercise facilitation and depression of motor evoked potentials in postpolio patients
Author(s) -
Samii A.,
LopezDevine J.,
Wasserman E.M.,
Dalakas M.C.,
Clark K.,
Grafman J.,
Hallett M.
Publication year - 1998
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199807)21:7<948::aid-mus16>3.0.co;2-m
Subject(s) - facilitation , isometric exercise , transcranial magnetic stimulation , medicine , depression (economics) , physical medicine and rehabilitation , stimulation , muscle fatigue , cardiology , physical therapy , electromyography , neuroscience , psychology , economics , macroeconomics
We studied the effects of exercise on motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation in healthy subjects and postpolio patients. Subjects performed repeated sets of isometric exercise until the muscle fatigued. In both groups, the mean MEP amplitude immediately after each exercise set was approximately twice that of the baseline amplitude, indicating similar postexercise facilitation, and after fatigue was approximately half that of the baseline amplitude, indicating similar postexercise depression. We conclude that the intracortical component of central fatigue is normal in postpolio patients. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:948–950, 1998.