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Training effects on soleus of cats spinal cord transected (T12–13) as adults
Author(s) -
Roy Roland R.,
Talmadge Robert J.,
Hodgson John A.,
Zhong Hui,
Baldwin Kenneth M.,
Edgerton V. Reggie
Publication year - 1998
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199801)21:1<63::aid-mus9>3.0.co;2-e
Subject(s) - isometric exercise , cats , soleus muscle , spinal cord , medicine , myosin , anatomy , atrophy , treadmill , cardiology , anesthesia , physical medicine and rehabilitation , endocrinology , chemistry , skeletal muscle , biochemistry , psychiatry
Adult spinal cord transected (T12–13) cats were trained for 30 min/day, 5 days/week to either step on a treadmill (Stp‐T) or stand (Std‐T) for ∼5 months. Training ameliorated soleus atrophy and enhanced maximum force capability compared to nontrained (N‐T) spinal cats, with Stp‐T being significantly different from N‐T. Isometric twitch speed and maximum rate of shortening were unaffected by training; the soleus of all spinal groups was significantly faster than control. There was an elevation in myosin adenosine triphosphatase activity and a shift toward faster myosin heavy chain and fiber type compositions in N‐T and Std‐T, but not Stp‐T cats. Thus, rhythmical activity involving muscle length and force changes (stepping) was more effective than a similar amount of a more static activity (standing). This specificity related to the type of training should be considered when developing rehabilitative strategies following spinal cord injury. © 1998 John Wiley & Sons, Inc. Muscle Nerve, 21: 63–71, 1998.