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Recurrent polyradiculoneuropathy with the 17p11.2 deletion
Author(s) -
Le Forestier Nadine,
LeGuern Eric,
Coullin Philippe,
Birouk Nazha,
Maisonobe Thierry,
Brice Alexis,
Léger Jean Marc,
Bouche Pierre
Publication year - 1997
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199709)20:9<1184::aid-mus16>3.0.co;2-t
Subject(s) - polyradiculoneuropathy , medicine , pediatrics , guillain barre syndrome
Hereditary neuropathy with liability to pressure palsies (HNPP) classically occurs as recurrent focal neuropathy. We report the first known instance of HNPP manifesting, over a 15‐year period, as a recurrent sensorimotor polyneuropathy and confirmed by the presence of the PMP‐22 gene deletion. We suggest that the molecular study of the 17p11.2 region could be an effective non invasive investigative tool in cases of chronic recurrent polyneuropathy associated with episodes of nerve palsy. © 1997 John Wiley & Sons, Inc. Muscle Nerve 20:1184–1186, 1997