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Neuromyotonia and type I myofiber predominance in amyloidosis
Author(s) -
Gutmann Laurie,
Gutmann Ludwig,
Schochet Sydney S.
Publication year - 1996
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199610)19:10<1338::aid-mus12>3.0.co;2-q
Subject(s) - myocyte , muscle biopsy , anatomy , amyloidosis , pathology , medicine , biopsy , biology
A case of amyloidosis presented with neuromyotonia and marked predominance of type I myofibers as documented by biopsy of an enlarged anterior tibialis muscle. This likely represents conversion of type II fibers to type I from continuous neuromyotonic stimulation. This transformation is well described to occur in animal models and this case represents a unique human example. Enlarged muscles likely reflected pseudohypertrophy. © 1996 John Wiley & Sons, Inc.