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Isolated vitamin E deficiency
Author(s) -
Jackson Carlayne E.,
Amato Anthony A.,
Barohn Richard J.
Publication year - 1996
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199609)19:9<1161::aid-mus12>3.0.co;2-y
Subject(s) - ataxia , vitamin e deficiency , medicine , malabsorption , peripheral neuropathy , polyneuropathy , gait ataxia , dysarthria , vitamin , endocrinology , vitamin e , vitamin a deficiency , pediatrics , gastroenterology , audiology , retinol , diabetes mellitus , biology , biochemistry , psychiatry , antioxidant
A 22‐year‐old man presented with progressive gait instability, tremor, and dysarthria since childhood. Electrophysiologic studies revealed a sensorimotor polyneuropathy. Laboratory studies documented vitamin E deficiency; however, no gastrointestinal, hepatic, or lipoprotein disorder could be identified. Vitamin E therapy normalized the serum level, but there was no neurologic improvement. Isolated vitamin E deficiency, in the absence of lipid malabsorption, should be considered in the evaluation of children and adults with ataxia and peripheral neuropathy. © 1996 John Wiley & Sons, Inc.