Premium
Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis
Author(s) -
Phoenix Joanne,
Betal Dibendu,
Roberts Neil,
Helliwell Timothy R.,
Edwards Richard H.T.
Publication year - 1996
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199603)19:3<302::aid-mus4>3.0.co;2-h
Subject(s) - magnetic resonance imaging , muscle biopsy , ultrasound , biopsy , muscle tissue , medicine , anatomy , pathology , radiology
Information about changes in muscle composition has to date been primarily restricted to histological examination of biopsy samples or qualitative assessment of images obtained using a variety of techniques (e.g., ultrasound, CT, and MRI). We describe the development of a quantitative method for the analysis of muscle composition using MR T 2 relaxation time mapping and image analysis. This approach provides an objective means of studying muscle and, when used in conjunction with force production measurements, may provide an accurate measure of response to muscle therapy. © 1996 John Wiley & Sons, Inc.