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Single‐fiber electromyography in diabetic peripheral polyneuropathy
Author(s) -
Bril Vera,
Werb Marsha R.,
Greene Douglas A.,
Sima Anders A.F.
Publication year - 1996
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/(sici)1097-4598(199601)19:1<2::aid-mus1>3.0.co;2-j
Subject(s) - medicine , reinnervation , electromyography , diabetes mellitus , nerve conduction velocity , diabetic neuropathy , cardiology , tibialis anterior muscle , polyneuropathy , peripheral , surgery , endocrinology , skeletal muscle , physical medicine and rehabilitation
In this study we examined the value of single‐fiber electromyography (SFEMG) in assessing the degree of reinnervation in diabetic patients with clinical neuropathy. Relationships between reinnervation and the degree of metabolic control, and/or duration of diabetes were examined. Thirty‐six insulin‐dependent diabetics and 54 non‐insulin‐dependent diabetics underwent SFEMG examination of the tibialis anterior muscle, as well as conventional nerve conduction studies of the upper and lower limbs. All patients examined exhibited some abnormality of SFEMG even in the presence of normal nerve conduction studies found in 18% of patients. In diabetic patients, the jitter in the tibialis anterior muscle correlated positively with glycosylated hemoglobin; whereas lower limb nerve conduction studies did not correlate with this measure of diabetic control. These data suggest that SFEMG is a sensitive measure of nerve function and reinnervation and that it may reflect the dynamic changes in metabolic status in diabetic patients. © 1996 John Wiley & Sons, Inc.