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Benzodiazepine analogues. Part 19. 1 H and 13 C NMR spectroscopic studies of 2‐phenyl‐1,4‐ and 1,5‐benzoheterazepinethione derivatives
Author(s) -
Mphahlele Malose J.,
Kaye Perry T.
Publication year - 2000
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(200003)38:3<207::aid-mrc595>3.0.co;2-6
Subject(s) - chemistry , flavanone , chemical shift , proton nmr , medicinal chemistry , stereochemistry , organic chemistry , flavonoid , antioxidant
Selected 1,4‐ and 1,5‐benzoheterazepinones, prepared by the Schmidt rearrangement of flavanone analogues, were converted to the corresponding thiolactam derivatives using phosphorus pentasulfide. The proton and carbon chemical shifts of the thiolactam derivatives are compared with those of their lactam precursors. Copyright © 2000 John Wiley & Sons, Ltd.