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Structural characterization and dynamic NMR studies of a new peracylated macrocyclic diterpene
Author(s) -
Günther Gábor,
Martinek Tamás,
Dombi György,
Hohmann Judit,
Vasas Andrea
Publication year - 1999
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199905)37:5<365::aid-mrc461>3.0.co;2-b
Subject(s) - diterpene , chemistry , dichloromethane , stereochemistry , spectral analysis , molecule , two dimensional nuclear magnetic resonance spectroscopy , characterization (materials science) , carbon 13 nmr , organic chemistry , spectroscopy , nanotechnology , solvent , physics , quantum mechanics , materials science
A heptaester of a new diterpene alcohol was isolated from the dichloromethane extract of the whole plant of Euphorbia esula L. A detailed NMR and mass spectral analysis revealed that its structure is ( E )‐(2 R * , 3 R * , 4 S * , 5 R * , 7 S * , 8 R * , 9 S * , 13 R * , 15 R * )‐2,3,5,8,9‐pentaacetoxy‐7‐isobutanoyloxy‐14‐oxojatropha‐6(17),11‐diene. Its conformation was studied in three different solutions. The temperature dependence of the spectral parameters revealed conformational changes through internal rotation of the macrocycle part of the molecule. Copyright © 1999 John Wiley & Sons, Ltd.