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Determination by 1D NOE studies of the stereochemistry of a tricyclic 2‐hydroxytetrahydrofuran derivative obtained by hydroformylation of (1 R )‐(‐)‐myrtenol
Author(s) -
Sirol S.,
Gorrichon J.P.,
Kalck P.,
Nieto P. M.,
Commenges G.
Publication year - 1999
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199902)37:2<127::aid-mrc429>3.0.co;2-7
Subject(s) - chemistry , hydroformylation , tricyclic , derivative (finance) , stereochemistry , organic chemistry , computational chemistry , catalysis , rhodium , financial economics , economics
The structure of a new, optically pure 2‐hydroxytetrahydrofuran tricyclic compound resulting from the hydroformylation of (1 R )‐(−)‐myrtenol was resolved by one‐ and two‐dimensional 1 H and 13 C NMR. The configurations of the three new asymmetric centres are discussed on the basis of J (H,H) coupling constants, NOE measurements and molecular modelling. Copyright © 1999 John Wiley & Sons, Ltd.