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Application of HSQC to the measurement of homonuclear coupling constants, J (H,H)
Author(s) -
Simova Svetlana
Publication year - 1998
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199807)36:7<505::aid-omr300>3.0.co;2-h
Subject(s) - homonuclear molecule , chemistry , heteronuclear single quantum coherence spectroscopy , coupling constant , proton , spin (aerodynamics) , nuclear magnetic resonance , coupling (piping) , proton spin crisis , two dimensional nuclear magnetic resonance spectroscopy , nuclear physics , stereochemistry , physics , molecule , quantum mechanics , thermodynamics , organic chemistry , mechanical engineering , engineering
It is demonstrated that HSQC gives considerably simpler multiplets than HMQC, allowing precise extraction of proton–proton coupling constants. Application of a spin‐locking pulse prior to acquisition yields pure‐phase 13 C decoupled multiplets. The combined use of coupled and refocused HSQC allows second‐order structure of the proton multiplets to be avoided in favourable cases. © 1998 John Wiley & Sons, Ltd.