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13 C NMR spectral characterization of some antimalarial tricyclic quinolone derivatives
Author(s) -
Dominguez Jose N.,
Charris Jaime E.,
Basante William,
Mendez Bernardo
Publication year - 1998
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199806)36:6<454::aid-omr249>3.0.co;2-v
Subject(s) - chemistry , quinolone , carbon 13 nmr , tricyclic , plasmodium falciparum , stereochemistry , proton nmr , two dimensional nuclear magnetic resonance spectroscopy , combinatorial chemistry , biochemistry , antibiotics , malaria , immunology , biology
We report the 13 C NMR chemical shifts of some active quinolones against Plasmodium falciparum , namely 3‐amino‐9‐phenyl‐1 H ‐pyrazolo[3,4‐ b ]quinolones and 2,4‐diamino‐10‐phenylpyrimido[4,5‐ b ]quinolones. They were characterized and assigned on the basis of 13 C– 1 H (short and long‐range) correlated spectra. © 1998 John Wiley & Sons, Ltd.