Premium
NMR study of C ‐ and N ‐trimethylsilylazole derivatives
Author(s) -
Larina Lyudmila I.,
Sorokin Mikhail S.,
Albanov Aleksandr I.,
Elokhina Valenti.,
Protsuk Nadezhda I.,
Lopyrev Valentin A.
Publication year - 1998
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199802)36:2<110::aid-omr224>3.0.co;2-f
Subject(s) - chemistry , tautomer , methanol , trimethylsilyl , nuclear magnetic resonance spectroscopy , carbon 13 nmr , spectroscopy , computational chemistry , medicinal chemistry , organic chemistry , physics , quantum mechanics
C ‐ and N ‐trimethylsilylazole derivatives were studied by 1 H, 13 C and 29 Si NMR spectroscopy. Degenerated prototropic tautomerism of 4‐trimethylsilylpyrazole in methanol and the silylotropy of 1‐trimethylsilyl‐4‐methylpyrazole in a neat liquid were investigated for the first time. 3‐ and 5‐tautomers of 3(5)‐methylpyrazole in a ratio of 54:46 were found in methanol by use 13 C NMR spectroscopy ( T c =230 K, Δ G c ≠ =10 kcal mol ‐1 ). © 1998 John Wiley & Sons, Ltd.