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Heteronuclear Edited Gradient Selected 1D and 2D NOE Spectra: Determination of the NOE Effect between Chemically Equivalent Protons
Author(s) -
Wagner Ronald,
Berger Stefan
Publication year - 1997
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199703)35:3<199::aid-omr55>3.0.co;2-1
Subject(s) - heteronuclear molecule , chemistry , heteronuclear single quantum coherence spectroscopy , two dimensional nuclear magnetic resonance spectroscopy , spectral line , pulsed field gradient , chemical shift , pulse sequence , nuclear overhauser effect , nuclear magnetic resonance , analytical chemistry (journal) , stereochemistry , nuclear magnetic resonance spectroscopy , molecule , chromatography , organic chemistry , physics , astronomy
With gradient selected HSQC‐NOESY spectra it is possible to detect the NOE effect between protons which have the same chemical shift either due to symmetry or due to accidental overlap. The discrimination of the equivalent sites is achieved by allowing one site to couple with 13 C in natural abundance. The suppression of unwanted signals is performed with pulse field gradient selection. Both 2D and selective 1D methods are shown. © 1997 by John Wiley & Sons, Ltd.