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2D 17 O, 1 H Chemical Shift Correlation Spectroscopy
Author(s) -
Schulte J.,
Lauterwein J.
Publication year - 1996
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199609)34:9<703::aid-omr942>3.0.co;2-q
Subject(s) - chemistry , ether , diethylene glycol , molecule , formate , proton , methyl formate , spectroscopy , relaxation (psychology) , organic chemistry , ethylene glycol , methanol , catalysis , psychology , social psychology , physics , quantum mechanics
Two‐dimensional 17 O, 1 H chemical shift correlation experiments were performed by polarization transfer via the 1 J (OH) coupling in 2‐hydroxymethyltetrahydrofuran and diethylene glycol monomethyl ether, and also via different 2 J (OH) couplings in methyl formate. The experiments were most useful in the discrimination between hydroxyl and ether oxygen resonances. However, their application seems to be limited to small molecules with 17 O relaxation times longer than ca . 5 ms. Further, large substrate concentrations are needed, in addition to high temperatures to keep the viscosity low and aprotic solvents to keep proton exchange low.