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Structural Aspects of Permethylated Cyclodextrins and Comparison with their Parent Oligosaccharides, as Derived from Unequivocally Assigned 1 H and 13 C NMR Spectra in Aqueous Solutions
Author(s) -
Botsi Antigone,
Yannakopoulou Konstantina,
Hadjoudis Eugene,
Perly Bruno
Publication year - 1996
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199606)34:6<419::aid-omr900>3.0.co;2-1
Subject(s) - chemistry , aqueous solution , nmr spectra database , solid state , nuclear magnetic resonance spectroscopy , spectral line , carbon 13 nmr , proton nmr , cyclodextrin , organic chemistry , computational chemistry , stereochemistry , physics , astronomy
The complete assignments of the 1 H and 13 C NMR spectra of α‐, β‐ and γ‐cyclodextrins (CDs) and their permethylated derivatives were derived from dedicated experiments. Existing literature data were complemented with detailed analyses, including unequivocal assignment of the methoxy groups. The structures of the macrocycles in solution, as derived from the NMR data, resemble those in the solid state. The increased distortions observed for the larger permethylated CDs are expected to affect seriously their complexing ability.