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19 F NMR of Proton‐Containing Solids
Author(s) -
Carss Steven A.,
Scheler Ulrich,
Harris Robin K.,
Holstein Peter,
Fletton Richard A.
Publication year - 1996
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/(sici)1097-458x(199601)34:1<63::aid-omr839>3.0.co;2-y
Subject(s) - chemistry , dephasing , fluorine 19 nmr , solid state nuclear magnetic resonance , nuclear magnetic resonance , carbon 13 nmr satellite , magic angle spinning , fluorine , nuclear magnetic resonance spectroscopy , dipole , electromagnetic shielding , magic angle , analytical chemistry (journal) , molecular physics , stereochemistry , organic chemistry , condensed matter physics , physics , quantum mechanics
Using three fluorinated steroids as examples, it is demonstrated that for simple multi‐fluorinated organic molecules single‐pulse and cross‐polarization magic‐angle spinning experiments with proton decoupling are both feasible and informative. Spinning sideband manifolds are used to obtain shielding tensor components, and shielding tensor information is also obtained from static lineshape analysis. Dipolar dephasing and rotational resonance effects are illustrated, and fluorine spin–lattice relaxation times have been measured. Spin‐diffusion effects are demonstrated for one compound via 2‐D spin‐exchange experiments. In addition, one compound is shown to exhibit polymorphism. Fluorine‐19 solution‐state NMR spectral information is also presented, for comparison with the accrued solid‐state NMR data.