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Ex vivo astroglial‐induced radial glia express in vivo markers
Author(s) -
Colombo J.A.,
Napp M.I.
Publication year - 1996
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/(sici)1097-4547(19961215)46:6<674::aid-jnr4>3.0.co;2-c
Subject(s) - ex vivo , in vivo , biology , laminin , cerebral cortex , neuroglia , cortex (anatomy) , astrocyte , neuroscience , microbiology and biotechnology , pathology , central nervous system , medicine , genetics , extracellular matrix
Ex vivo induction of radial‐like glia has been previously reported to occur following exposure of cerebral cortex subcultures from fetal origin to cerebral cortex astroglial conditioned medium. The present report further confirms similarities between in vivo and ex vivo radial glia, using additional criteria: adhesion of primary cell dissociates to glial processes, with presumptive cell migration along them, punctate labelling for laminin, and immunolabelling with Rat‐401 antisera. © 1996 Wiley‐Liss, Inc.