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Sentinel node biopsy for melanoma in the head and neck region
Author(s) -
Jansen Liesbeth,
Koops Heimen Schraffordt,
Nieweg Omgo E.,
Doting M. H. Edwina,
Kapteijn B. Acca E.,
Balm Alfons J. M.,
Vermey Albert,
Plukker John Th.,
Hoefnagel Cornelis A.,
Piers D. Albertus,
Kroon Bin B. R.
Publication year - 2000
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/(sici)1097-0347(200001)22:1<27::aid-hed5>3.0.co;2-z
Subject(s) - sentinel node , medicine , biopsy , melanoma , head and neck , neck dissection , mucosal melanoma , sentinel lymph node , radiology , dissection (medical) , surgery , cancer , cancer research , breast cancer
Abstract Background Lymphatic drainage in the head and neck region is known to be particularly complex. This study explores the value of sentinel node biopsy for melanoma in the head and neck region. Methods Thirty consecutive patients with clinically localized cutaneous melanoma in the head and neck region were included. Sentinel node biopsy was performed with blue dye and a gamma probe after preoperative lymphoscintigraphy. Average follow‐up was 23 months (range, 1–48). Results In 27 of 30 patients, a sentinel node was identified (90%). Only 53% of sentinel nodes were both blue and radioactive. A sentinel node was tumor‐positive in 8 patients. The sentinel node was false‐negative in two cases. Sensitivity of the procedure was 80% (8 of 10). Conclusions Sentinel node biopsy in the head and neck region is a technically demanding procedure. Although it may help determine whether a neck dissection is necessary in certain patients, further investigation is required before this technique can be recommended for the standard management of cutaneous head and neck melanoma. © 2000 John Wiley & Sons, Inc. Head Neck 22: 27–33, 2000.