z-logo
Premium
End results of a prospective trial on elective lateral neck dissection vs type III modified radical neck dissection in the management of supraglottic and transglottic carcinomas
Author(s) -
Ricardo R. Brentani,
Luiz Paulo Kowalski,
José Francisco Soares,
Humberto Torloni,
Raimunda N. Pereira,
Mauro Kasuo Ikeda,
Roberto P. Andrade,
José Magrin,
Roberto E.V. Miguel,
Carlos Roberto dos Santos,
Leda M.B. Saba,
J.V. Salvajoli,
María Paula Curado,
José Carlos Oliveira,
Paula O. Montandon,
Márcio Martins Machado,
Giovana F. Denofrio,
Waldyr Castro Quinta,
Rene B. Alvarez,
Rita C.G. Alencar,
Benedito Valdecir de Oliveira,
Gyl Henrique Albrecht Ramos,
Leonardo Santos Antunes,
Jozias Andrade Sobrinho,
Abrão Rapoport,
Marcos Brasilino de Carvalho,
Antonio Fava,
José F. Gois Filho,
José Francisco Salles Chagas,
Jossi Ledo Kanda,
Flávio M. Gripp,
Marcelo Haddad Ribas,
Ivan S. Castro,
Joni M.S. Oliveira,
José Alberto Oliveira,
Ricardo Cruz de Carvalho,
Laércio B. Araújo,
Paulo Pontes,
Luís Carlos Gregório,
Márcio Abrahäo,
Onivaldo Cervantes,
Marcos B. Paiva,
Werner S. Hebbel,
Reginaldo Raimundo Fujita,
Pedro Motta,
Roberto Araújo Segreto,
Roberto da Silva Camargo,
Marcos S. Menten,
Eric Victor de Oliveira Ferreira,
Celso Alberto Chassot
Publication year - 1999
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/(sici)1097-0347(199912)21:8<694::aid-hed3>3.0.co;2-b
Subject(s) - medicine , neck dissection , surgery , larynx , prospective cohort study , carcinoma
Background Either modified type III radical neck dissection (MRND) or lateral neck dissections (LNDs) are considered valid treatments for patients with laryngeal carcinoma with clinically negative neck findings (N0). The object of this prospective study was to compare complications, neck recurrences, and survival results of elective MRND and LND on the management of laryngeal cancer patients. Patients and Methods This prospective randomized study began in 1990, and patient accrual was closed on December 1993. A total of 132 patients was included in the trial. All patients had previously untreated T2–T4 N0 M0 supraglottic or transglottic squamous cell carcinoma. No significant imbalance was found between groups with respect to demographic, clinical, pathologic, and other therapeutic variables. Seventy‐one patients were given MRNDs (13 bilateral) and 61 were given LNDs (18 bilateral). Results The false‐negative rate was 26%, and most positive nodes were sited at levels II and III. Complications and period of hospitalization were similar in both groups. There were 6 ipsilateral neck recurrences (4 in the MRND group, and 2 in the LND group). The 5‐year actuarial survival calculated by Kaplan‐Meier method was 72.3% in the MRND group and 62.4% in the LND group (log‐rank test p = .312). Conclusions The rate of false‐negative nodes in supraglottic and transglottic carcinomas was 26%, and most positive nodes were at levels II and III. The rates of 5‐year overall survival, neck recurrences, and complications were similar in both groups. These results confirm the efficacy of lateral neck dissection in the elective treatment of the neck in patients with supraglottic and transglottic carcinomas. © 1999 John Wiley & Sons, Inc. Head Neck 21: 694–702, 1999.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here