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Primary T‐cell lymphoma of the thyroid
Author(s) -
Coltrera Marc D.
Publication year - 1999
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/(sici)1097-0347(199903)21:2<160::aid-hed10>3.0.co;2-f
Subject(s) - thyroid lymphoma , medicine , thyroid , vincristine , lymphoma , anaplastic carcinoma , thyroiditis , differential diagnosis , pathology , prednisolone , radiation therapy , cyclophosphamide , chemotherapy
Background The routine use of immunocytochemical analysis has led to the recognition that many thyroid neoplasms previously diagnosed as anaplastic or small cell carcinomas are actually lymphomas of the thyroid. The great majority are B‐cell lymphomas which can be associated with Hashimoto's thyroiditis. In spite of this, thyroid lymphomas are still not commonly recognized as a significant part of thyroid differential diagnosis. Methods A rare case of a primary T‐cell lymphoma of the thyroid gland is presented along with general clinical history and physical findings which should make the practitioner suspicious of a thyroid lymphoma. The usefulness of radiology scans and fine‐needle aspiration are discussed. Results Both prognosis and treatment options are very different for thyroid lymphomas and anaplastic carcinoma. Conclusions Cyclophosphamide/adriamycin/vincristine/prednisolone chemotherapy/radiotherapy regimens have proven to be very effective for most thyroid lymphomas. © 1999 John Wiley & Sons, Inc. Head Neck 21: 160–163, 1999.