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Fine‐needle aspiration cytology of primary granulosa cell tumor of the adrenal gland: A case report
Author(s) -
Hameed Arif,
Coleman Robert L.
Publication year - 2000
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(200002)22:2<107::aid-dc10>3.0.co;2-1
Subject(s) - medicine , exploratory laparotomy , granulosa cell , pathology , adrenal gland , uterus , hysterectomy , differential diagnosis , ovary , gynecology , anatomy
Extraovarian granulosa cell tumors are extremely rare. We report on a primary granulosa cell tumor of the adrenal gland. A 69‐yr‐old African‐American female presented with a 1‐yr history of irregular uterine bleeding and a palpable right abdominal mass. CT scan showed a 9.0‐cm suprarenal mass as well as an enlarged uterus. CT‐guided fine‐needle aspiration (FNA) cytology of the adrenal mass was interpreted as a malignant neoplasm. She underwent exploratory laparotomy, right nephrectomy, and hysterectomy with bilateral salpingo‐oophorectomy. The gross, histologic, and immunohistochemical findings of the adrenal mass were characteristic of a granulosa cell tumor. The uterus contained multiple leiomyomas. The endometrium showed simple hyperplasia. Both fallopian tubes and ovaries showed no pathologic abnormality. There was no evidence of tumor elsewhere. Although rare, extraovarian granulosa cell tumor should be considered in the differential diagnosis of adrenal tumors in women showing the FNA features described herein, especially when there is evidence of excessive estrogen production. Diagn. Cytopathol. 2000;22:107–109. © 2000 Wiley‐Liss, Inc.