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Cytologic diagnosis of a melanotic neuroectodermal tumor of infancy occurring in the cranial bones
Author(s) -
Rege J.D.,
Shet Tanuja,
Sawant H.V.,
Naik L.P.
Publication year - 1999
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199910)21:4<280::aid-dc10>3.0.co;2-2
Subject(s) - medicine , pathology , skull , neuroblast , cytology , maxilla , lesion , epithelioid cell , surgical excision , histopathological examination , anatomy , radiology , immunohistochemistry , biology , neurogenesis , microbiology and biotechnology
Melanotic neutroectodermal tumor of infancy (MNTI) is a rare, usually benign tumor commonly occurring in the maxilla. MNTIs at unusual sites like the cranium clinically mimic malignant small round cell tumors. Consequently, a correct preoperative cytologic diagnosis of MNTI at these sites helps in the surgical management of the patient. We report on a cytologically diagnosed case of MNTI in the frontotemporal region of the skull in an infant. Aspirates from the lesion were cellular, with a bimodal population mainly of small neuroblast‐like cells admixed with a few large epithelioid cells with melanin granules. In the present case, following the cytologic diagnosis a wide local excision was carried out, and the histologic examination confirmed the cytologic diagnosis. Diagn. Cytopathol. 1999;21:280–283. © 1999 Wiley‐Liss, Inc.