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Fine‐needle sampling findings in 26 carcinoma ex pleomorphic adenomas: Diagnostic pitfalls and clinical considerations
Author(s) -
Klijanienko Jerzy,
ElNaggar Adel K.,
Vielh Philippe
Publication year - 1999
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199909)21:3<163::aid-dc3>3.0.co;2-2
Subject(s) - medicine , sampling (signal processing) , carcinoma , pathology , carcinoma ex pleomorphic adenoma , radiology , pleomorphic adenoma , salivary gland , filter (signal processing) , computer science , computer vision
Preoperative fine‐needle samplings (FNS) of 26 histologically proven carcinoma ex pleomorphic adenomas (24 primary tumors and 2 local recurrences in 24 patients) were retrospectively reviewed in order to evaluate their cytologic characteristics. Histologically, 17 were high‐grade and 9 were low‐grade carcinomas; 10 carcinomas were intratumoral (in situ), and 16 were infiltrative. A cytologic diagnosis of malignancy was established in 13 (50%) cases, 2 (7.7%) were suspicious, and 11 (42.3%) were negative for malignancy (10 pleomorphic adenomas, 1 inflammation). The majority (76.5%) of high‐grade carcinomas were correctly diagnosed by FNS, regardless of invasiveness. Paradoxically, most (77.8%) negative results were encountered in low‐grade carcinomas. Accurate diagnosis of malignancy on FNS is achieved in high‐grade tumors and low sensitivity may cause interpretative difficulties in low‐grade tumors. Diagn. Cytopathol. 1999; 21:163–166. © 1999 Wiley‐Liss, Inc.