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Salivary gland neoplasms with basaloid cell features: Report of two cases diagnosed by fine‐needle aspiration cytology
Author(s) -
Tawfik Ossama,
Tsue Terance,
Pantazis Cooley,
Nuckols Douglas,
Younes Souhad,
Webb Patricia
Publication year - 1999
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199907)21:1<46::aid-dc13>3.0.co;2-n
Subject(s) - pathology , medicine , cytopathology , adenocarcinoma , nuclear atypia , atypia , cytology , salivary gland , fine needle aspiration , adenoma , fine needle aspiration cytology , basal (medicine) , immunohistochemistry , cancer , biopsy , insulin
Basal‐cell adenoma and basal‐cell adenocarcinoma of the salivary gland are rare tumors. Fine‐needle aspiration cytology of these tumors, particularly those of basal‐cell adenocarcinoma, has rarely been described in the literature. In this report, we describe the clinical, cytomorphologic, histopathologic, and immunohistochemical features of basal‐cell adenoma and its malignant counterpart, basal‐cell adenocarcinoma, in 2 patients. Fine‐needle aspiration specimens from both tumors contained abundant cohesive groups of neoplastic cells. Basaloid cells were prominent in both tumors; however, there were significant cytologic atypia, hyperchromasia, and increased nuclear‐to‐cytoplasmic ratio in basal‐cell adenocarcinoma. Review of the literature and cytomorphologic distinction between both tumors and others are discussed. Diagn. Cytopathol. 1999;21:46–50. © 1999 Wiley‐Liss, Inc.