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Peripheral T‐cell lymphoma presenting as ascites: A case report and review of the literature
Author(s) -
VakarLópez Funda,
Yang Mary
Publication year - 1999
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199906)20:6<382::aid-dc11>3.0.co;2-l
Subject(s) - medicine , hepatosplenomegaly , pathology , ascites , abdomen , lymphoma , t cell lymphoma , population , carcinoembryonic antigen , gastroenterology , radiology , disease , environmental health , cancer
Here we report an unusual case of T‐cell lymphoma presenting as ascites. A 49‐yr‐old woman was admitted to the hospital for abdominal discomfort associated with increasing abdominal girth over the course of 3 mo. She also complained of nausea, vomiting, and diarrhea. On physical examination, a tense and distended abdomen and edema of the lower extremities were noted. Neither hepatosplenomegaly nor lymphadenopathy was found. A CT scan of the abdomen and pelvis showed a large abdominal/pelvic mass surrounding the small bowel and omentum and small nodes in the para‐aortic and mesenteric regions. The cytospin prepared from the peritoneal fluid was hypercellular and composed of a population of monotonous, noncohesive cells with a high nuclear/cytoplasmic ratio and a single prominent central nucleolus. The cells were positive for leukocyte common antigen and Leu‐22 (CD43) but negative for keratin, L26, UCHL‐1, kappa, lambda, CD3, Ki‐1 (CD30), S‐100, and carcinoembryonic antigen. Morphologic and immunologic findings were suggestive of T‐cell immunoblastic lymphoma. Peripheral T‐cell lymphomas rarely present as ascites; this case demonstrates the value of effusion cytology in making this diagnosis. Diagn. Cytopathol. 1999;20:382–384. © 1999 Wiley‐Liss, Inc.