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Lymphoepithelial cyst (lEC) of the pancreas: Cytomorphology and differential diagnosis on fine‐needle aspiration (FNA)
Author(s) -
Mandavilli Srinivas R.,
Port John,
Ali Syed Z.
Publication year - 1999
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199906)20:6<371::aid-dc8>3.0.co;2-s
Subject(s) - medicine , pathology , fine needle aspiration , differential diagnosis , pancreas , cyst , histiocyte , pancreatic pseudocyst , giant cell , cytopathology , lesion , biopsy , cytology , endocrinology
Abstract Lymphoepithelial cyst (LEC) of the pancreas is an extremely rare benign entity. We describe the cytopathologic findings of such a lesion in a 49‐yr‐old woman who was examined for epigastric pain. A trans‐esophageal ultrasound‐guided fine‐needle aspiration of a pancreatic mass disclosed an intimate mixture of squamous epithelial cells and small, mature lymphocytes in a background of keratinaceous debris, anucleate squames, and multinucleated histiocytes. On histopathologic examination, a subsequent resection showed a multiloculated cystic lesion with a stratified squamous epithelial lining surrounded by well‐formed lymphoid tissue, suggestive of LEC. The differential diagnosis includes other pancreatic pseudocysts, dermoid cyst, mucinous cystic neoplasms, adenosquamous carcinoma, and metastatic squamous cell carcinoma. Diagn. Cytopathol. 1999;20:371–374. © 1999 Wiley‐Liss, Inc.