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Granular‐cell tumor of the esophagus: Report of a case with a cytologic diagnosis based on esophageal brushing
Author(s) -
Córdoba A.,
Manrique M.,
Zozaya E.,
Martinez Peñuela J.M.,
GomezDorronsoro M.,
Querol I.
Publication year - 1998
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199812)19:6<455::aid-dc10>3.0.co;2-s
Subject(s) - medicine , granular cell tumor , esophagus , biopsy , differential diagnosis , lesion , cytology , cytopathology , radiology , endoscopy , pathology , surgery , immunohistochemistry
We report a case of granular‐cell tumor (GCT) in the esophagus. This is a rare location for this tumor and only 80 cases have been described. The tumor was diagnosed in a 24‐yr‐old woman with epigastralgia. Endoscopic examination revealed a submucosal ulcerated lesion. The smears derived from esophageal brushings contained clusters of granular cells. Histologic examination of the endoscopic biopsy provided diagnostic confirmation of GCT. To our knowledge, this is the first reported case of esophageal GCT in which the characteristic tumor cells were seen in the endoscopic brushing material. This case demonstrates that a cytologic diagnosis of GCT is possible if the lesion is ulcerated and/or brushing is subsequent to taking the biopsy. Although rare in the esophagus, GCT should be considered in the differential diagnosis of esophageal neoplasms. Diagn. Cytopathol. 1998;19:455–457. © 1998 Wiley‐Liss, Inc.