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Skeletal metastases from a granulosa‐cell tumor of the ovary: Report of a case diagnosed by fine‐needle aspiration cytology
Author(s) -
Thirumala Seshadri D.,
Putti Thomas C.,
Medalie Neil S.,
Wasserman Patricia G.
Publication year - 1998
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199811)19:5<375::aid-dc13>3.0.co;2-o
Subject(s) - medicine , ovary , cytology , fine needle aspiration cytology , pathology , gynecology
We report on the fine‐needle aspiration cytological findings of a metastatic granulosa‐cell tumor of the ovary to bone. The patient had undergone resection of a primary ovarian granulosa‐cell tumor 15 yr prior to her last admission. Recently she injured her right hip, sustained after a fall. CT examination revealed hypodense lesions involving the posterior body and the right pedicle of the L1 vertebra. The aspirate from the bone yielded a highly cellular smear, composed of round to oval cells with scanty cytoplasm. Many of the cells revealed the presence of nuclear grooves. In areas, the cells were arranged in clusters resembling Call‐Exner bodies. The rarity of skeletal metastases from granulosa‐cell tumors can cause diagnostic difficulty in diagnosing this entity. Accurate clinical data, radiological findings, and cytological features are important in arriving at the correct diagnosis. Diagn. Cytopathol. 1998;19:375–377. © 1998 Wiley‐Liss, Inc.