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Endometrial intraepithelial carcinoma diagnosed by brush cytology and P53 immunostaining, and confirmed by hysterectomy
Author(s) -
Maksem John A.,
Lee Steve S.
Publication year - 1998
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199810)19:4<284::aid-dc11>3.0.co;2-j
Subject(s) - medicine , immunostaining , hysterectomy , carcinoma , endometrial hyperplasia , pathology , atypical hyperplasia , cytology , endometrium , gynecology , immunohistochemistry
Endometrial intraepithelial carcinoma (EIC) is associated with tumors of high nuclear grade and usually is seen in endometria without complex atypical hyperplasia. Tumor cells oftentimes show an accumulation of mutant p53 protein. This report describes a case of EIC detected by endometrial brush cytology and p53 immunostaining, and confirmed by hysterectomy. Diagn. Cytopathol. 1998;19:284–287. © 1998 Wiley‐Liss, Inc.