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Cytologic distinction between bronchioalveolar carcinoma and reactive/reparative respiratory epithelium: A cytomorphometric analysis
Author(s) -
Fiorella Russell M.,
Gurley Steven D.,
Dubey Susan
Publication year - 1998
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199810)19:4<270::aid-dc8>3.0.co;2-e
Subject(s) - medicine , pathology , respiratory system , carcinoma , cytology
Cytologically, the distinction between bronchioalveolar carcinoma and reactive/reparative processes of respiratory epithelium can be difficult. Retrospectively, we have identified 11 consecutive cases of bronchioalveolar carcinoma from the cytology files of University Missouri‐Kansas City/Truman Medical Center. On average, a combined 5.71 cytologic/histologic procedures were performed before reaching a definitive diagnosis for this group. An additional seven random cases of reactive/reparative respiratory cases of adult respiratory distress syndrome patients were used as a control. Cytomorphometric analysis was performed. The mean average nuclear diameter for the carcinoma group was 13.76 μm and for the reactive/reparative group was 13.29 μm. There was no statistical difference between the two groups (paired student t test, P < .05). It appears from our data that mean nuclear diameter is not a discriminator for the cytologic distinction between bronchioalveolar carcinoma and reactive/reparative respiratory epithelium and that the accepted cytologic parameters of for bronchioalveolar carcinoma are more valid. Diagn. Cytopathol. 1998;19:270–273. © 1998 Wiley‐Liss, Inc.