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Lymphocyte‐depleted Hodgkin's disease: Diagnostic challenges by fine‐needle aspiration
Author(s) -
Grosso Leonard E.,
Collins Brian T.,
Dunphy Cherie H.,
Ramos Ricardo R.
Publication year - 1998
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199807)19:1<66::aid-dc14>3.0.co;2-6
Subject(s) - medicine , fine needle aspiration , biopsy , differential diagnosis , disease , lymphoma , pathology , hodgkin lymphoma , cytopathology , cytology
The diagnosis of Hodgkin's disease by fine‐needle aspiration (FNA) can be problematic. A case of Hodgkin's disease, lymphocyte depleted subtype, sampled by FNA biopsy is presented. We describe the cytomorphologic features present in this unusual subtype of Hodgkin's disease and discuss the differential diagnosis. Immunohistochemical and morphologic findings of a subsequent biopsy specimen supported the diagnosis. Although FNA is an increasingly used diagnostic modality to evaluate tumors including malignant lymphomas, Hodgkin's disease remains, as in this case, a difficult diagnosis by FNA. Diagn. Cytopathol. 1998;19:66–69. © 1998 Wiley‐Liss, Inc.