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Fine‐needle aspiration cytology and immunocytochemistry of Hodgkin's disease, suppurative type
Author(s) -
Tani E.,
Ersöz C.,
Svedmyr E.,
Skoog L.
Publication year - 1998
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199806)18:6<437::aid-dc10>3.0.co;2-i
Subject(s) - medicine , pathology , immunocytochemistry , lymphoma , reed–sternberg cell , mononucleosis , fine needle aspiration , cytology , lymph node , differential diagnosis , biopsy , immunology , hodgkin lymphoma , virus
We describe 3 cases of Hodgkin's disease (HD) of unusual suppurative type, which were diagnosed on fine‐needle aspirates. The smears were dominated by neutrophils, macrophages, and cellular debris. Only a few large, atypical cells of Hodgkin and Reed‐Sternberg type were observed. The differential diagnoses of such smears include infectious mononucleosis, tuberculosis, metastatic lymph node involvement, non‐Hodgkin's large‐cell anaplastic Ki‐1‐positive lymphomas, T‐cell‐rich B‐cell lymphomas, and peripheral T‐cell lymphomas of mixed type. Immunocytochemistry identified the large atypical cells as CD 30 (BerH2)‐positive and negative for CD 45 (LCA) in cytospin material from 2 patients, which allowed a conclusive diagnosis of HD. Diagn. Cytopathol. 1998;18:437–440. © 1998 Wiley‐Liss, Inc.