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Is the cytologic diagnosis of esophageal glandular dysplasia feasible?
Author(s) -
Hughes Jonathan H.,
Cohen Michael B.
Publication year - 1998
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199804)18:4<312::aid-dc13>3.0.co;2-m
Subject(s) - medicine , dysplasia , cytology , pathology , radiology , general surgery
Barrett's esophagus is a premalignant condition in which the normal stratified squamous epithelium of the esophagus is replaced by metaplastic glandular epithelium. Patients with Barrett's esophagus are at increased risk for the development of esophageal adenocarcinoma. Because dysplasia precedes the development of frank adenocarcinoma, the cytologic detection of esophageal glandular dysplasia represents a potentially inexpensive and efficient means of monitoring disease progression to adenocarcinoma and identifying high‐risk patients. This article discusses the current status of exfoliative cytology as a screening test for glandular dysplasia of the esophagus. Diagn. Cytopathol. 1998;18:312–316. © 1998 Wiley‐Liss, Inc.