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Concomitant lymphoma and metastatic carcinoma in a lymph node: Diagnosis by fine‐needle aspiration biopsy in two cases
Author(s) -
Caraway Nancy P.,
Wojcik Eva M.,
Saboorian Housain M.,
Katz Ruth L.
Publication year - 1997
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199710)17:4<287::aid-dc9>3.0.co;2-9
Subject(s) - medicine , metastatic carcinoma , lymphoma , fine needle aspiration , concomitant , pathology , lymph node , biopsy , lymph node biopsy , carcinoma , cytopathology , population , cytology , environmental health
Concomitant lymphoma and metastatic carcinoma are an unusual occurrence in a lymph node. We report two patients in whom synchronous malignancies were diagnosed by fine‐needle aspiration biopsy (FNAB). In one case, the FNAB diagnoses of both small lymphocytic lymphoma and metastatic breast carcinoma were the initial diagnoses. In the second case, metastatic poorly differentiated squamous carcinoma was an unexpected finding in a patient with a history of small lymphocytic lymphoma. The aspirates in both cases showed two distinct cell populations, one consisting of a dispersed population of small uniform lymphoid cells and the other comprising large atypical single cells and cohesive clusters of epithelial cells. In both cases, the cytologic diagnoses were supported by immunohistochemical and flow cytometric studies. Diagn. Cytopathol. 1997;17:287–291, 1997. © 1997 Wiley‐Liss, Inc.