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Fine‐needle aspiration cytologic findings in a case of lymph node tumor of plasmacytoid monocytes
Author(s) -
Fontana P.,
Facchetti F.,
Fiaccavento S.
Publication year - 1997
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199707)17:1<57::aid-dc12>3.0.co;2-9
Subject(s) - pathology , medicine , fine needle aspiration , lymph node , h&e stain , cytopathology , cytology , infiltration (hvac) , nucleolus , lymph , biopsy , staining , nucleus , physics , psychiatry , thermodynamics
We present a unique case of fine‐needle aspiration (FNA) from a lymph node with subsequent histologic diagnosis of tumor of plasmacytoid monocytes (PMs). The patient had an associated myeloproliferative disease which terminated into an acute myelomonocytic leukemia. In a 95% ethanol‐fixed, hematoxylin‐eosin (H&E)‐stained smear, the tumor cells appeared monomorphic, medium sized, with oval to indented nuclei, finely stippled chromatin, and small nucleoli; the cytoplasm was scanty and slightly eccentric. The cytologic picture suggested some subtypes of small‐cell non‐Hodgkin's lymphomas or a leukemic infiltration. In the FNA specimen, the cells appeared immunocytochemically negative for some B‐ and T‐cell markers (MB2, L26, LN1, and UCHL1) and strongly positive to KP1, a known histyocyte‐macrophage and myeloid marker. The FNA differential diagnoses are discussed. Diagn. Cytopathol. 17:57–60, 1997. © 1997 Wiley‐Liss, Inc.