Premium
Papillary‐cystic tumor of the pancreas
Author(s) -
Remadi Sami,
Mac Gee William,
DoussisAnagnostopoulou Ipatia,
Berger Sophie Diebold,
Ismail Awatef
Publication year - 1996
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199612)15:5<398::aid-dc8>3.0.co;2-8
Subject(s) - medicine , pancreas , general surgery , papillary tumor , pathology
A case of papillary cystic tumor (PCT) of the pancreas in a 40‐yr‐old woman is reported. This rare neoplasm was discovered fortuitously by a CT‐scan examination for a palpable abdominal uterine leiomyoma. Percutaneous fine‐needle aspiration (FNA) of the pancreatic mass was performed under CT‐scan guidance. Cytologic examination of the material gave the diagnosis of PCT, which was confirmed by histologic examination of the resected tumor. Immunohistochemical staining showed a high degree of positivity to wide‐spectrum anticytokeratin and anticytokeratin 20, and a weak positivity to anti‐NSE antibody. In addition, the tumor cells were highly reactive for progesterone antibody, while they were negative for estrogen. These findings suggest a ductal origin for PCT, and also suggest that sex hormones may play a role in its growth, but not in its genesis. We emphasize the value of FNA cytologic features in the diagnosis of these rare tumors. Diagn Cytopathol 1996;15:398–402. © 1996 Wiley‐Liss, Inc.