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Tumoral calcium pyrophosphate dihydrate deposition disease: Cytopathologic findings on fine‐needle aspiration
Author(s) -
Allen Elizabeth A.,
Ali Syed Z.,
Erozan Yener S.
Publication year - 1996
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199611)15:4<349::aid-dc20>3.0.co;2-n
Subject(s) - medicine , fine needle aspiration , pathology , malignancy , cytopathology , calcium pyrophosphate , chondrocalcinosis , fine needle aspiration cytology , cytology , anatomy , calcium , biopsy , osteoarthritis , alternative medicine
Tumoral calcium pyrophosphate dihydrate deposition disease (CPPD) is a rare non‐neoplastic entity which mimics primary or metastatic soft‐tissue or skeletal malignancy. Fewer than a dozen cases have been reported in the literature with only histologic descriptions. We present cytologic findings of a unique case of CPPD in a 73‐year‐old black female with a history of end‐stage renal disease. A fine‐needle aspiration (FNA) was done on a 4 × 4‐cm neck mass which was clinically thought to be malignant. Cytopathologic examination showed numerous macrophages with markedly distended cytoplasm and containing multiple yellowish‐orange, short rhomboid crystals. These were strongly birefringent on polarized microscopy, consistent with CPPD crystals. Diagn Cytopathol 1996;15:349–351. © 1996 Wiley‐Liss, Inc.