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Metastatic neoplasms of the breast: Fine‐needle aspiration cytology of two cases
Author(s) -
Ferrara Gerardo,
Nappi Oscar
Publication year - 1996
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/(sici)1097-0339(199608)15:2<139::aid-dc12>3.0.co;2-i
Subject(s) - medicine , pathology , neoplasm , fine needle aspiration , metastatic carcinoma , leiomyosarcoma , cytopathology , cytology , carcinoma , biopsy
Even when clinical data strongly suggest the presence of a metastatic neoplasm in the breast, this occurrence almost invariably raises great problems in diagnostic pathology. Both cases presented here had a well‐recognized primitive neoplasm located elsewhere. Nonetheless, great importance was given to the application of ancillary techniques; the immunostains for “breast discriminants”—GCDFP15, HMFG1, and HMFG2—on tissue sections helped the recognition of a metastatic renal cell carcinoma; and the stains for S100 protein, smooth muscle actin, cytokeratins, and neurofilaments on cytologic material allowed the identification of a metastatic mediastinal leiomyosarcoma. Diagn Cytopathol 1996;15:139–143. © 1996 Wiley‐Liss, Inc.