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Improvement of red pigment/citrinin production ratio as a function of environmental conditions by monascus ruber
Author(s) -
Hajjaj H.,
Blanc P. J.,
Groussac E.,
Goma G.,
Uribelarrea J. L.,
Loubiere P.
Publication year - 1999
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/(sici)1097-0290(19990820)64:4<497::aid-bit12>3.0.co;2-q
Subject(s) - citrinin , monascus , pigment , aeration , monascus purpureus , chemistry , food science , photobioreactor , yield (engineering) , biomass (ecology) , botany , biology , mycotoxin , ecology , materials science , organic chemistry , metallurgy
The growth and metabolic behaviour of the filamentous fungus Monascus ruber were studied in submerged cultures under various aeration and agitation conditions. Improving the oxygen supply, by increasing either the air input or the agitation speed, resulted in modified metabolism: the biomass yield, the consumption of the nitrogen source (monosodium glutamate), and the production of secondary metabolites (red pigment and citrinin) all increased. However, the citrinin production increased more than that of the red pigment. In consequence, a low oxygen transfer coefficient was required to improve the red pigment/citrinin production ratio. © 1999 John Wiley & Sons, Inc. Biotechnol Bioeng 64: 497–501, 1999.