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Rapid biocatalytic polytransesterification: Reaction kinetics in an exothermic reaction
Author(s) -
Chaudhary Apurva K.,
Beckman Eric J.,
Russell Alan J.
Publication year - 1998
Publication title -
biotechnology and bioengineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 189
eISSN - 1097-0290
pISSN - 0006-3592
DOI - 10.1002/(sici)1097-0290(19980820)59:4<428::aid-bit5>3.0.co;2-i
Subject(s) - exothermic reaction , polymerization , activation energy , reaction calorimeter , kinetics , monomer , chemistry , reaction rate , thermodynamics , chemical kinetics , differential scanning calorimetry , polymer chemistry , bulk polymerization , order of reaction , phase (matter) , reaction mechanism , calorimetry , reaction rate constant , organic chemistry , radical polymerization , catalysis , polymer , physics , quantum mechanics
Biocatalytic polytransesterification at high concentrations of monomers proceeds rapidly and is accompanied by an increase in the temperature of the reaction mixture due to liberation of heat of reaction during the initial phase. We have used principles of reaction calorimetry to monitor the kinetics of polymerization during this initial phase, thus relating the temperature to the extent of polymerization. Rate of polymerization increases with the concentration of monomers. This is also reflected by the increase in the temperature of the reaction mixture. Using time‐temperature‐conversion contours, a differential method of kinetic analysis was used to calculate the energy of activation (∼15.1 Kcal/mol). © 1998 John Wiley & Sons, Inc. Biotechnol Bioeng 59:428–437, 1998.