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Occupational, environmental, and life‐style factors associated with the risk of hematolymphopoietic malignancies in women
Author(s) -
Miligi L.,
Costantini A. Seniori,
Crosignani P.,
Fontana A.,
Masala G.,
Nanni O.,
Ramazzotti V.,
Rodella S.,
Stagnaro E.,
Tumino R.,
Viganò C.,
Vindigni C.,
Vineis P.
Publication year - 1999
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/(sici)1097-0274(199907)36:1<60::aid-ajim9>3.0.co;2-z
Subject(s) - medicine , chronic lymphocytic leukemia , leukemia , lymphoma , multiple myeloma , population , etiology , disease , immunosuppression , risk factor , oncology , immunology , environmental health
Background: The etiology of lymphomas, leukemias, and multiple myeloma is still largely unknown. The known risk factors (ionizing radiation, solvent exposure, pesticide exposure, immunosuppression) explain only a small proportion of the cases that occur. Methods: We conducted a multicenter population‐based case‐control study on hematolymphopoietic malignancies in Italy and interviewed 2,011 women (1,183 cases and 828 controls). Results: There was a suggestion of a positive association between smoking and the risk of non‐Hodgkin's lymphoma + chronic lymphocytic leukemia. A slight increased risk of leukemias was observed among women using permanent hair dye. Housewives were at increased risk for leukemia and multiple myeloma. The risk of non‐Hodgkin's lymphomas + chronic lymphocytic leukemia, leukemias, multiple myeloma, and Hodgkin's disease increased among women employed as hairdressers and textile workers. Teachers were at increased risk for non‐Hodgkin's lymphomas + chronic lymphocytic leukemia, leukemias, and Hodgkin's disease. Conclusions: These results confirm previous associations and may provide additional clues to some determinants of hematolymphopoietic malignancies in women. Am. J. Ind. Med. 36:60–69, 1999. © 1999 Wiley‐Liss, Inc.