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Occupation and the risk of laryngeal cancer in Uruguay
Author(s) -
De Stefani Eduardo,
Boffetta Paolo,
Oreggia Fernando,
Ronco Alvaro,
Kogevinas Manolis,
Mendilaharsu Maria
Publication year - 1998
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/(sici)1097-0274(199806)33:6<537::aid-ajim3>3.0.co;2-n
Subject(s) - medicine , environmental health , cancer , logistic regression , relative risk , asbestos , larynx , laryngeal neoplasm , toxicology , surgery , confidence interval , materials science , metallurgy , biology
In a case‐control analysis involving 112 patients afflicted by laryngeal cancer and 509 controls diagnosed with cancers not related to tobacco and alcohol exposures, we studied the effects of type of employment and of substances present in the workplace on laryngeal cancer risk. Effects were measured relative to those never employed or never exposed to the substances. All analyses were controlled for age, tobacco smoking, and alcohol drinking through unconditional logistic regression and stratified analysis. Among job titles, butchers, vintners, bakers, and car assemblers presented elevated risks of laryngeal cancer (OR for butchers 2.8, 95% CL 1.1–7.2). Similarly, asbestos, mists from strong inorganic acids and pesticide exposures were associated with increased risks of laryngeal cancer (OR for strong acids 1.8, 95% 1.1–2.9). Am. J. Ind. Med. 33:537–542, 1998. © 1998 Wiley‐Liss, Inc.