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Chlorinated hydrocarbon solvents and biliary‐pancreatic cancer: Report of three cases
Author(s) -
Zarchy Thomas M.
Publication year - 1996
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/(sici)1097-0274(199609)30:3<341::aid-ajim12>3.0.co;2-w
Subject(s) - medicine , pancreatic cancer , hydrocarbon , carcinogen , cancer , gastroenterology , risk factor , pancreas , organic chemistry , chemistry
This paper describes three men, aged 45 years or younger, who developed cholangio, ampullary, and pancreatic cancer after prolonged heavy exposure to trichlorinated hydrocarbon solvents. Two of these patients had exposure to other potential carcinogens, and one had a strong family history of cancer. The association between chlorinated hydrocarbons and biliary‐pancreatic cancer has also been suggested by other reports in the recent literature. Exposure to trichlorinated hydrocarbon solvents is a risk factor for the development of biliary and pancreatic cancer. © 1996 Wiley‐Liss, Inc.